Exploring how RNA methylation modifications influence colorectal cancer prognosis and immunotherapy response through dynamic epigenetic regulation.
Discover how the RNF43 G659fs mutation in colorectal cancer creates a therapeutic vulnerability to PI3K/mTOR inhibitors, opening new precision medicine approaches.
Exploring the role of USP29 as a key oncogene driving tumorigenesis in colorectal cancer through protein stabilization and cellular pathway regulation.
Discover how TRIM29 reprograms glucose metabolism in colorectal cancer through pyruvate kinase manipulation and the Warburg effect.
Discover how NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer through JNK signaling pathway modulation.
Exploring the critical role of RNF43 mutations in serrated colorectal neoplasia and their implications for cancer treatment.